No-Fenol in a great-tasting tutti-frutti flavored tablet!
Easy to chew tablet form lets you take No-Fenol anywhere. Tastes so good kids will love it as a snack! Great for school lunches.
No-Fenol was developed by Dr. Devin Houston in response to parent's request for a product that would allow their children to eat fruits and vegetables without the problems thought to be associated with polyphenolic compounds. Initial response from many parents indicate that for many, No-Fenol does allow the addition of these foods to the diet without complications.
- Unique Formulation to Assist in Digestion of Phenolic Foods
- High Amounts of Xylanase and Cellulase Enzymes
- Phytase Present to Increase Availability of Minerals and Nutrients
All plants contain some degree of phenolic compounds. The phenol structure itself is ubiquitous in nature, and is actually essential to many of life's processes. Current thinking by many is that some subset of children on the PDD spectrum have difficulty in the processing of phenolic compounds, which may present as behavioral problems and physical symptoms such as red ears and cheeks, and dark circles under the eyes. While the basic mechanism behind this phenomenon is not well defined, it is thought that perhaps the phenolic compounds become "trapped" in some part of a metabolic cycle, presumbably involved with various detoxification pathways.
The research literature indicates that some phenolic compounds are modified by the addition of carbohydrate groups to their structures, which may inhibit their crossing into cells and being metabolized. The current hypothesis for why No-Fenol may help is through the ability of the enzymes in this product to remove the carbohydrate groups from the phenols, thus allowing normal processing by the detoxification pathways. There is no evidence that No-Fenol directly modifies phenolic structures. Indeed, the success of No-Fenol in allowing the addition of phenolic foods back into the diet of children with PDD may result in a re-evaluation of the basis of the phenol "problem".
Xylanase is the major component of No-Fenol, and is an enzyme used to breakdown the structural components of plant cell walls, which are primarily very complex carbohydrates. Xylanase is used in the juice industry to extract more juice from fruit pulp fibers. At least one reference indicates that polyphenolic compounds are actually increased by treatment with xylanase. Based on this reference and the fact that No-Fenol has allowed "phenol-sensitive" individuals to ingest phenolic foods, HNI now believes that the phenol issue is much more complex than previously thought, and may not be due so much to the presence of phenols as to the specific structure of these phenols.
Parental feedback indicates that No-Fenol allows many to eat some amount of phenolic foods without adverse effects on behavior or physical symptoms. A wide variation existed as to amounts and types of these foods that could be consumed. Those children with chronic constipation reported more frequent bowel movements. Some parents also reported that children could better tolerate food colorings and certain over the counter medications, such as cold medications and analgesic agents.
Reported Side Effects
Side effects were noted with initial use of No-Fenol and included hyperactivity, more frequent urination, and increased sweating. In most cases, these effects resolved over time or with adjustment of enzyme dose or decreased use of other supplements. Some parents noted a correlation between these effects and increased yeast "die-off", which can produce similar side effects. In some cases, stools were softer and less formed, which may be a result of the enzymes decreasing the viscosity of the intestinal contents, as noted in animal studies.
Contraindications for Enzyme Supplementation
This product may not be appropriate for those with known allergies to Aspergillus enzyme proteins, though non-specific mold allergies do not necessarily preclude use of fungal enzymes. Consult your medical doctor for further advice, and err on the side of caution. Those with known anaphylactic allergic reactions to fungal proteins should NOT ingest fungal-derived enzymes.
No upper limit has been established for enzyme dosing, and animal studies found no toxicity at dosing as high as 80,000 FXU per kilogram of body weight per day for 13 weeks. No-Fenol is recommended primarily for those with known sensitivities to phenolic compounds. Recommended dosing is from 1 - 2 tablets with phenolic foods, but not necessarily with every meal. Some have found satisfactory results with once or twice per day dosing, indicating that optimal dosing may be dependent upon many factors.
One tablet is equal to 1/3 of 1 capsule; 1 or 2 tablets should suffice for those meals high in phenolic compounds. More tablets can be taken as desired. Tablets may be crushed, using care not to inhale enzyme powder.
|Serving Size: 1 Tablet|
|Amount Per Serving
% Daily Value
|CereCalaseTM (473 MU)
(hemicellulase, beta-glucanase, phytase)
*Daily Value Not Established
Other Ingredients: Fructose, Xylitol, Stearic Acid (vegetalbe source), Silicon Dioxide, Sodium Chroride.
Contains NO added starch, dairy, soy, wheat, yeast, gluten, artificial flavors, or animal derivatives. HNI uses only the highest quality FDA GRAS approved plant-based enzymes available.
Suggested use: As a dietary supplement, chew 1 - 4 tablets with meals or snacks. Dosing is by size of meal.
Store in a cool, dry place away from direct light and humid conditions.
Keep container closed and stored at room temperature. May also be kept frozen (below 20 deg F) but do NOT keep in refrigerator.
CereCalaseTM is a trademark of National Enzyme Company.